Sunday, 20th May 2018
20 May 2018

Pathology Mcqs 8 – Gastrointestinal Tract & Hepato – Biliary Pathology

Pathology MCQs 8 – Gastrointestinal Tract & Hepato – Biliary Pathology

  1. All the following conditions lead to conjugated hyperbilirubinemia except
    1. Gilbert syndrome
    2. Dubin-Johnson syndrome
    3. Rotor syndrome
    4. Cholestatic jaundice
      1. Ans(1)
  2. In Dubin syndrome, the following accumulates in lysosomes
    1. Epinephrine
    2. Norepinephrine
    3. Bilirubin
    4. Hemosiderin
      1. Ans(1)
  3. Not sure about Crigler-Najjar syndrome I
    1. Complete absence of UFT1A1 activity
    2. Liver darkly pigmented
    3. Autosomal recessive
    4. Hereditary unconjugated bilirubinemia
      1. Ans(2)
  4. Crigler – Najjar syndrome results due to the absence of the hepatic enzyme
    1. UDP – glucuronosyl Transferase
    2. Alanine Transferase
    3. Aspartate Transferase
    4. UDH – Glucose dehydrogenase
      1. Ans(1)
  5. Glucuronosyl transferase is absent in
    1.  Dubin-Johnson syndrome
    2. Rotor syndrome
    3. Crigler – Najjar syndrome I
    4. Crigler – Najjar syndrome II
      1. Ans(3)
  6. Predominantly unconjugated hyperbilirubinemia is seen in
    1. Gilbert’s syndrome
    2. Cirrhosis
    3. Drug-induced hepatitis
    4. All the above
      1. Ans(1)
  7. Microvesicular fatty change of liver caused by
    1. Benzene
    2. Yellow phosphorus
    3. Carbon tetrachloride
    4. Rifampicin
      1. Ans(2)
  8. Mallory hyaline is found in all except
    1. Congenital hepatic fibrosis
    2. Primary biliary cirrhosis
    3. Alcoholic hepatitis D.Wilson’s disease
      1. Ans(1)
  9. All are seen in acute viral hepatitis except
    1. Councilman bodies
    2. Mallory bodies
    3. Ballooning degeneration
    4. Hepatic cell necrosis
      1. Ans(2)
  10. Hallmark of irreversible liver damage is
    1. Bridging necrosis
    2. Piecemeal necrosis
    3. Periportal fibrosis
    4. Ballooning degeneration
      1. Ans(3)
  11. All are associated with fibrosis except
    1. Focal nodular hyperplasia
    2. Nodular regenerative hyperplasia
    3. Fibrolamellar carcinoma
    4. Alcoholic liver disease
      1. Ans(2)
  12. Emphysema with cirrhosis is seen in
    1. Wilson’s disease
    2. Hemochromatosis
    3. Alpha 1 – antitrypsin deficiency
    4. CMV infection
      1. Ans(3)
  13. In hemochromatosis of pancreas, hemosiderin is deposited in
    1. Islet cell
    2. Acinar cells
    3. Interstitial stroma
    4. All the above
      1. Ans(4)
  14. All are true about Wilson’s disease except
    1. Increased ceruloplasmin levels
    2.  Coomb’s negative hemolytic anemia
    3. Serum copper level may be low, N or increased
    4. Liver copper content increased
      1. Ans(1)
  15. All the following lab findings are true in Wilson’s disease except
    1. Serum copper levels always decreased
    2. Decreased in serum ceruloplasmin
    3. Increase in hepatic copper content
    4. Increased urinary copper excretion
      1. Ans(1)
  16. Alfa-fetoprotein is increased in
    1. Hemangioma liver
    2. Hepatocellular carcinoma
    3. hepatic adenoma
    4. Hepatoma
      1. Ans(2)
  17. Major risk factor for hepatocellular carcinoma
    1. Cirrhosis
    2. Alcoholic hepatitis
    3. Schistosomiasis
    4. Fasciolopsis buski
      1. Ans(1)
  18. Migratory thrombophlebitis is seen in
    1. Acute pancreatitis
    2. Chronic pancreatitis
    3. Carcinoma pancreas
    4. Skin cancer
      1. Ans(3)
  19. Features of Crohn’s disease A/E
    1. Non-caseating granulomas
    2. Entro – cutaneous fistula formation
    3. Transmural involvement of intestine
    4. Continous lesions
      1. Ans(4)
  20. The following polyp has an increased tendency to become malignant
    1. Hyperplastic polyps
    2. Hamartomatous polyps
    3. Peutz – Jeghers polyps
    4. Villous adenoma
      1. Ans(4)
  21. All are true about Gardner syndrome except
    1. Intestinal polyps
    2. Thyroid carcinoma
    3. CNS tumors
    4. Osteomas
      1. Ans(3)
  22. Conjugated hyperbilirubinemia is seen in
    1. Criaggler – Najjar syndrome
    2. Stone in CBD
    3. Rh incompatibility
    4. Hemolysis of any cause
      1. Ans(2)
  23. Most common symptom of primary biliary cirrhosis is
    1. Jaundice
    2. Abdomen Pain
    3. Pruritus
    4. Fatigue
      1. Ans(3)

Read previous MCQs

Pathology MCQs 2 – Neoplasia
Pathology MCQs 6 – Disorders of White Blood Cells

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